One of the world’s greatest train rides, the Train to the Clouds (Tren a las Nubes), takes visitors on a scenic 269-mile (434-kilometer) journey, ascending 13,842 feet (4,220 meters), passing through 21 tunnels and crossing over 29 bridges and 13 viaducts. The climax of the trip comes as the train crosses La Polvorilla viaduct, which pans a massive desert canyon.
Departing from the city of Salta, the train makes its way through the Cordillera de los Andes, passes through the Valle de Lerma and Quebrada del Toro and finishes in La Puna. Bilingual guides in each car offer insight into the surrounding topography and help with any altitude
Along the way, the train makes a stop at the small town of San Antonio de los Cobres, where you can get out, stretch your legs and purchase handicrafts and souvenirs from the indigenous locals.
The round-trip journey on the Train to the Clouds takes 15 hours and departs early, so be prepared for a very long day.