Art and architecture reign supreme in the Renaissance city of Florence. The cobblestone streets have hardly changed since the 17th century, and walking tours will take you through hidden plazas (piazze), over the Ponte Vecchio, and past the Brunelleschi-designed Duomo. Opt for skip-the-line tickets to see the Galleria dell'Accademia di Firenze and Uffizi Gallery, home to some of the world’s most famous artwork. And be sure to allow plenty of time for leisurely meals featuring the bounty of the Tuscan hills surrounding the city.