Meet your private driver for the day in the port of Civitavecchia when you disembark from your ship. Drive into the center of Rome to meet your guide for the day, an expert in archaeology or art and history.
Begin in Vatican City and enjoy skip-the-line tickets to avoid the often long queues outside the Vatican Museums. See the highlights of the Vatican's immense collection of artifacts and art, finishing with Michelangelo's incomparable frescoes in the Sistine Chapel.
Next, travel to one of Rome's most famous monuments, the Colosseum. Admire the impressive amphitheater from the outside before continuing to the Pantheon. Walk inside one of the city's best-preserved ancient structures.
Stop for a sample of Italian gelato, and then visit the Villa Farnesina to see paintings by Raphael. Finish your day with stops to see the Trevi Fountain and Spanish Steps, after which you'll be returned to the Civitavecchia port.