Find your guide and tour group waiting at the Plaça Catalunya, where you will see the Gothic Cathedral, famous for having taken six centuries to finish. You'll also see the Roman Wall's remains at Plaça Ramon Berenguer.
Proceed to the Picasso Museum for skip-the-line access at this popular attraction. Spend 45 minutes on a guided tour, getting to know the artist's style, his work and the highlights of his biography. See 4,200 pieces of art housed in 5 interconnected medieval palaces, including the 1957 series "Las Meninas" and some of his Blue Period works. After the guided tour, spend some free time exploring on your own.
Embark on your walking tour of the Gothic Quarter, getting the feel of the neighborhood as you pound the pavement (and cobblestone) between several highlights. At Plaça del Rei, visit the Saló del Tinell, the 15th-century Santa Àgata’s chapel, and the Tower of King Martí.
Continue to Plaça Sant Jaume, where the city's two major Roman roads once crossed. It is now the center of Barcelona's political activity. End your tour here, just a 2-minute walk from La Rambla, where you can continue exploring on your own.