Perhaps one of the more underrated tours you can take, run by a local company out of Salta. A really personal experience. In the small group of 15 or fewer people, you really experience the landscape and culture as if you were driving yourself, listening to an audiobook. Our tour guide Eduardo was extremely knowledgeable and certainly had a good answer for any and all questions you have. His English was excellent, and gave the tour in both English and Spanish. Sometimes tour guides will slowly move towards one language during the tour but he treated the whole group equally the entire time.
Such a spectacular drive, gorgeous scenery, a real taste of the local culture. The wine tour and tasting was good, but what really made the tour special were all the little experiences we had along the way.