Begin with pickup at your hotel in Panama City, then travel 1.5 hours east of the city to the Mamoni River. On your way to the launch point, visit EcoFarms Panama, a conservation organization that preserves tropical rainforest in the Mamoni River area, and pass through remaining strips of primary and secondary rainforest, now important sites for research into tropical biodiversity.
Water levels in the Mamoni River fluctuate seasonally, from an annual high in November to the low-water point in April or May. The river guide will choose boats based on the water level: groups use smaller, 11-foot (3.35-meter) rafts and inflatable kayaks from December through February, inflatable kayaks from March through April, then rafts and inflatable kayaks from May through June.
Paddle through moderate to intense rapids, with a few portages at impassable points, including a scenic Class V+ waterfall that's a highlight of the Mamoni River. You’ll reach the takeout point after roughly 6 hours of river time, then dry off for the return trip to Panama City. This tour concludes with drop-off at your hotel at 5:30pm.